Interleukin-12 Is Required for Control of the Growth of Attenuated Aromatic-Compound-Dependent Salmonellae in BALB/c Mice: Role of Gamma Interferon and Macrophage Activation

The attenuated S. typhimurium SL3261 (aroA) strain causes mild infections in BALB/c mice. We were able to exacerbate the disease by administering anti-interleukin-12 (IL-12) antibodies, resulting in bacterial counts in the spleens and livers of anti-IL-12-treated mice that were 10- to 100-fold highe...

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Библиографические подробности

Опубликовано в::	Infect Immun
Главные авторы:	Mastroeni, Pietro, Harrison, J. A., Robinson, J. H., Clare, S., Khan, S., Maskell, D. J., Dougan, G., Hormaeche, C. E.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1998
Предметы:	Bacterial Infections
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9746577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.10.4767-4776.1998
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