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Differential effects of the protein cofactor on the interactions between an RNase P ribozyme and its target mRNA substrate

RNase P from Escherichia coli is a tRNA-processing enzyme and consists of a catalytic RNA subunit (M1 RNA) and a protein component (C5 protein). M1GS, a gene-targeting ribozyme derived from M1, can cleave a herpes simplex virus 1 mRNA efficiently in vitro and inhibit its expression effectively in vi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hsu, Amy W., Kilani, Ahmed F., Liou, Kwa, Lee, Jarone, Liu, Fenyong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC108434/
https://ncbi.nlm.nih.gov/pubmed/10931926
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