Chargement en cours...
Id2 Mediates Tumor Initiation, Proliferation, and Angiogenesis in Rb Mutant Mice
The inhibitor of differentiation Id2 is a target of the retinoblastoma (Rb) protein during mouse embryogenesis. In Rb(+/−) mice, LOH at the wild-type Rb allele initiates pituitary adenocarcinoma, a tumor derived from embryonic melanotropes. Here we identify a critical role for Id2 in initiation, gro...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084294/ https://ncbi.nlm.nih.gov/pubmed/15831462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3563-3574.2005 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|