Dok-R Mediates Attenuation of Epidermal Growth Factor-Dependent Mitogen-Activated Protein Kinase and Akt Activation through Processive Recruitment of c-Src and Csk

Dok-R has previously been shown to associate with the epidermal growth factor receptor (EGFR) and become tyrosine phosphorylated in response to EGF stimulation. The recruitment of Dok-R to the EGFR, which is mediated through its phosphotyrosine binding (PTB) domain, results in attenuation of mitogen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Van Slyke, Paul, Coll, Mariano Loza, Master, Zubin, Kim, Harold, Filmus, Jorge, Dumont, Daniel J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2005
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084282/
https://ncbi.nlm.nih.gov/pubmed/15831486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3831-3841.2005
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