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Myc/Max/Mad regulate the frequency but not the duration of productive cell cycles
Upregulation of the proto-oncoprotein Myc, a basic, helix–loop–helix, leucin zipper domain transcription factor has profound consequences on cell proliferation, cell growth and apoptosis. Cell cultures of somatic c-myc(–/–) rat fibroblasts show extremely prolonged doubling times of 52 h. Using time-...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084169/ https://ncbi.nlm.nih.gov/pubmed/11743027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve251 |
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