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CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein
The ubiquitin–proteasome system catalyses the immediate destruction of misfolded or impaired proteins generated in cells, but how this proteolytic machinery recognizes abnormality of cellular proteins for selective elimination remains elusive. Here, we report that the C-terminus of Hsc70-interacting...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084164/ https://ncbi.nlm.nih.gov/pubmed/11743028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve246 |
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