Stable gene expression from a mammalian artificial chromosome

We have investigated the potential of PAC-based vectors as a route to the incorporation of a gene in a mammalian artificial chromosome (MAC). Previously we demonstrated that a PAC (PAC7c5) containing α-satellite DNA generated mitotically stable MACs in human cells. To determine whether a functional...

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Detalhes bibliográficos
Main Authors: Grimes, Brenda R., Schindelhauer, Dirk, McGill, Nio I., Ross, Andrew, Ebersole, Thomas A., Cooke, Howard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084075/
https://ncbi.nlm.nih.gov/pubmed/11571265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve187
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