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Transcription termination factor TTF-I exhibits contrahelicase activity during DNA replication
In mammals, sequence-specific termination of DNA replication within the ribosomal RNA genes is catalyzed by a defined DNA–protein complex that includes transcription termination factor I (TTF-I). Here we show that TTF-I acts as a polar contrahelicase contrary to the intrinsic 3′→5′ helicase activity...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2002
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083968/ https://ncbi.nlm.nih.gov/pubmed/11818337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf027 |
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