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Aneuploid colon cancer cells have a robust spindle checkpoint
Colon cancer cells frequently display minisatellite instability (MIN) or chromosome instability (CIN). While MIN is caused by mismatch repair defects, the lesions responsible for CIN are unknown. The observation that CIN cells fail to undergo mitotic arrest following spindle damage suggested that mu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083941/ https://ncbi.nlm.nih.gov/pubmed/11454737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve127 |
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