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Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae
Cholesterol-sphingolipid rich plasma membrane domains, known as rafts, have emerged as important regulators of signal transduction. The adipocyte insulin receptor (IR) is localized to and signals via caveolae that are formed by polymerization of caveolins. Caveolin binds to IR and stimulates signall...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083929/ https://ncbi.nlm.nih.gov/pubmed/11751579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf010 |
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