A role for chemokine receptor transactivation in growth factor signaling

Complex cell responses require the integration of signals delivered through different pathways. We show that insulin-like growth factor (IGF)-I induces specific transactivation of the G(i)-coupled chemokine receptor CCR5, triggering its tyrosine phosphorylation and Gα(i) recruitment. This transactiv...

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Bibliographic Details
Main Authors: Mira, Emilia, Lacalle, Rosa Ana, González, Manuel A., Gómez-Moutón, Concepción, Abad, José Luis, Bernad, Antonio, Martínez-A., Carlos, Mañes, Santos
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083823/
https://ncbi.nlm.nih.gov/pubmed/11258708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve027
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