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EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye
β-catenin/Armadillo are transcriptional co-activators that mediate Wnt signalling in normal development. Activated forms of β-catenin are oncogenic. We have constructed mutant forms of Drosophila Armadillo which correspond to common human oncogenic mutations, and find them to activate Armadillo cons...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083815/ https://ncbi.nlm.nih.gov/pubmed/11258709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve019 |
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