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EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye

β-catenin/Armadillo are transcriptional co-activators that mediate Wnt signalling in normal development. Activated forms of β-catenin are oncogenic. We have constructed mutant forms of Drosophila Armadillo which correspond to common human oncogenic mutations, and find them to activate Armadillo cons...

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Autors principals: Freeman, Matthew, Bienz, Mariann
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083815/
https://ncbi.nlm.nih.gov/pubmed/11258709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve019
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