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Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3-kinase activity
Rab5 and phosphatidylinositol 3-kinase (PI3K) have been proposed to co-regulate receptor endocytosis by controlling early endosome fusion. However, in this report we demonstrate that inhibition of epidermal growth factor (EGF)-stimulated PI3K activity by expression of the kinase-deficient PI3K p110...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2001
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083802/ https://ncbi.nlm.nih.gov/pubmed/11252727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve005 |
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