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Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3-kinase activity

Rab5 and phosphatidylinositol 3-kinase (PI3K) have been proposed to co-regulate receptor endocytosis by controlling early endosome fusion. However, in this report we demonstrate that inhibition of epidermal growth factor (EGF)-stimulated PI3K activity by expression of the kinase-deficient PI3K p110...

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Detalhes bibliográficos
Main Authors: Chen, Xinmei, Wang, Zhixiang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083802/
https://ncbi.nlm.nih.gov/pubmed/11252727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve005
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