Inducible Nitric Oxide Synthase-Deficient Mice Develop Enhanced Type 1 Cytokine-Associated Cellular and Humoral Immune Responses after Vaccination with Attenuated Schistosoma mansoni Cercariae but Display Partially Reduced Resistance

High levels of nitric oxide (NO) are produced by inducible nitric oxide synthase (iNOS) in response to activating signals from Th1-associated cytokines and play an important role in cytotoxicity and cytostasis against many pathogenic microorganisms. In addition to its direct effector function, NO se...

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Bibliografiska uppgifter

I publikationen:	Infect Immun
Huvudupphov:	James, Stephanie L., Cheever, Allen W., Caspar, Patricia, Wynn, Thomas A.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1998
Ämnen:	Fungal and Parasitic Infections
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9673227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.8.3510-3518.1998
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