Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

Ku86 together with Ku70, DNA-PKcs, XRCC4 and DNA ligase IV forms a complex involved in repairing DNA double-strand breaks (DSB) in mammals. Yeast Ku has an essential role at the telomere; in particular, Ku deficiency leads to telomere shortening, loss of telomere clustering, loss of telomeric silenc...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Samper, Enrique, Goytisolo, Fermín A., Slijepcevic, Predrag, van Buul, Paul P.W., Blasco, María A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2000
Ábhair:
Scientific Reports
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083725/
https://ncbi.nlm.nih.gov/pubmed/11256607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd051
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla