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Construction and Vaccine Potential of Acapsular Mutants of Erysipelothrix rhusiopathiae: Use of Excision of Tn916 To Inactivate a Target Gene

We previously showed that acapsular transposon Tn916 mutants of Erysipelothrix rhusiopathiae are avirulent for mice. In this study, we constructed nonreverting acapsular mutants and examined the vaccine potential of the mutants in mice. A representative acapsular transposon mutant, 33H6, was plated...

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Auteurs principaux: Shimoji, Yoshihiro, Mori, Yasuyuki, Sekizaki, Tsutomu, Shibahara, Tomoyuki, Yokomizo, Yuichi
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC108339/
https://ncbi.nlm.nih.gov/pubmed/9632592
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