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Construction and Vaccine Potential of Acapsular Mutants of Erysipelothrix rhusiopathiae: Use of Excision of Tn916 To Inactivate a Target Gene

We previously showed that acapsular transposon Tn916 mutants of Erysipelothrix rhusiopathiae are avirulent for mice. In this study, we constructed nonreverting acapsular mutants and examined the vaccine potential of the mutants in mice. A representative acapsular transposon mutant, 33H6, was plated...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Shimoji, Yoshihiro, Mori, Yasuyuki, Sekizaki, Tsutomu, Shibahara, Tomoyuki, Yokomizo, Yuichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108339/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632592/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.7.3250-3254.1998
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