Mucosal Delivery of Murine Interleukin-2 (IL-2) and IL-6 by Recombinant Strains of Lactococcus lactis Coexpressing Antigen and Cytokine

Lactococcus lactis is a nonpathogenic and noncolonizing bacterium which is being developed as a vaccine delivery vehicle for immunization by mucosal routes. To determine whether lactococci can also deliver cytokines to the immune system, we have constructed novel constitutive expression strains of L...

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Главные авторы: Steidler, Lothar, Robinson, Karen, Chamberlain, Lisa, Schofield, Karin M., Remaut, Erik, Le Page, Richard W. F., Wells, Jeremy M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1998
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC108331/
https://ncbi.nlm.nih.gov/pubmed/9632584
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