Mucosal Delivery of Murine Interleukin-2 (IL-2) and IL-6 by Recombinant Strains of Lactococcus lactis Coexpressing Antigen and Cytokine

Lactococcus lactis is a nonpathogenic and noncolonizing bacterium which is being developed as a vaccine delivery vehicle for immunization by mucosal routes. To determine whether lactococci can also deliver cytokines to the immune system, we have constructed novel constitutive expression strains of L...

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Pubblicato in:	Infect Immun
Autori principali:	Steidler, Lothar, Robinson, Karen, Chamberlain, Lisa, Schofield, Karin M., Remaut, Erik, Le Page, Richard W. F., Wells, Jeremy M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108331/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.7.3183-3189.1998
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