Opsonic Antibodies to the Surface M Protein of Group A Streptococci in Pooled Normal Immunoglobulins (IVIG): Potential Impact on the Clinical Efficacy of IVIG Therapy for Severe Invasive Group A Streptococcal Infections

The surface M protein of group A streptococci (GAS) is one of the major virulence factors for this pathogen. Antibodies to the M protein can facilitate opsonophagocytosis by phagocytic cells present in human blood. We investigated whether pooled normal immunoglobulin G (IVIG) contains antibodies tha...

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Bibliographic Details
Main Authors: Basma, Hesham, Norrby-Teglund, Anna, McGeer, Allison, Low, Donald E., El-Ahmedy, Omar, Dale, James B., Schwartz, Benjamin, Kotb, Malak
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108192/
https://ncbi.nlm.nih.gov/pubmed/9573118
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