Opsonic Antibodies to the Surface M Protein of Group A Streptococci in Pooled Normal Immunoglobulins (IVIG): Potential Impact on the Clinical Efficacy of IVIG Therapy for Severe Invasive Group A Streptococcal Infections

The surface M protein of group A streptococci (GAS) is one of the major virulence factors for this pathogen. Antibodies to the M protein can facilitate opsonophagocytosis by phagocytic cells present in human blood. We investigated whether pooled normal immunoglobulin G (IVIG) contains antibodies tha...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Basma, Hesham, Norrby-Teglund, Anna, McGeer, Allison, Low, Donald E., El-Ahmedy, Omar, Dale, James B., Schwartz, Benjamin, Kotb, Malak
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.5.2279-2283.1998
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