Soluble CD14 Activates Monocytic Cells Independently of Lipopolysaccharide

The glycoprotein CD14 acts as a receptor for lipopolysaccharide (LPS), either when anchored in the myeloid cell membrane (mCD14) or as a soluble molecule (sCD14) in serum. sCD14-LPS complexes activate cells devoid of mCD14. However, the role of sCD14 independent of LPS is unknown. Therefore, the eff...

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Bibliographic Details
Main Authors: Landmann, Regine, Link, Susanne, Sansano, Sebastiano, Rajacic, Zarko, Zimmerli, Werner
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108190/
https://ncbi.nlm.nih.gov/pubmed/9573116
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