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Increased Leptin Expression in Mice with Bacterial Peritonitis is Partially Regulated by Tumor Necrosis Factor Alpha

Plasma leptin and ob gene mRNA levels were increased in mice following bacterial peritonitis, and blocking an endogenous tumor necrosis factor alpha (TNF-α) response blunted the increase. However, plasma leptin concentrations did not correlate with the associated anorexia. We conclude that leptin ex...

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Udgivet i:Infect Immun
Principais autores: Moshyedi, Armin K., Josephs, Michael D., Abdalla, Eddie K., MacKay, Sally L. D., Edwards, Carl K., Copeland, Edward M., Moldawer, Lyle L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108125/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9529118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.4.1800-1802.1998
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