Leptin Elicits LTC4 Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD2 Receptors

Leptin is a cytokine, produced mainly by mature adipocytes, that regulates the central nervous system, mainly to suppress appetite and stimulate energy expenditure. Leptin also regulates the immune response by controlling activation of immunomodulatory cells, including eosinophils. While emerging as...

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Hlavní autoři:	Natália R. T. Amorim, Tatiana Luna-Gomes, Marcos Gama-Almeida, Glaucia Souza-Almeida, Claudio Canetti, Bruno L. Diaz, Peter F. Weller, Patricia Torres Bozza, Clarissa M. Maya-Monteiro, Christianne Bandeira-Melo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-09-01
Edice:	Frontiers in Immunology
Témata:	leptin eosinophil prostaglandin D2 leukotriene C4 CCR3 CCL5
On-line přístup:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02139/full
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