The N-Terminal Part of the Enzyme Component (C2I) of the Binary Clostridium botulinum C2 Toxin Interacts with the Binding Component C2II and Functions as a Carrier System for a Rho ADP-Ribosylating C3-Like Fusion Toxin

The binary actin–ADP-ribosylating Clostridium botulinum C2 toxin consists of the enzyme component C2I and the binding component C2II, which are separate proteins. The active component C2I enters cells through C2II by receptor-mediated endocytosis and membrane translocation. The N-terminal part of C2...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Barth, H., Hofmann, F., Olenik, C., Just, I., Aktories, K.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1998
Fag:	Molecular and Cellular Pathogenesis
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9529054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.4.1364-1369.1998
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