Defective Nitric Oxide Effector Functions Lead to Extreme Susceptibility of Trypanosoma cruzi-Infected Mice Deficient in Gamma Interferon Receptor or Inducible Nitric Oxide Synthase

Trypanosoma cruzi, the causative agent of Chagas’ disease, induces an innate and adaptive host immune response during the acute phase of infection. These responses were analyzed by comparing mouse lines deficient for the gamma interferon (IFN-γ) receptor (IFN-γR(−/−)) or deficient for inducible nitr...

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Bibliografiske detaljer

Udgivet i:	Infect Immun
Principais autores:	Hölscher, Christoph, Köhler, Gabriele, Müller, Uwe, Mossmann, Horst, Schaub, Günter A., Brombacher, Frank
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1998
Fag:	Fungal and Parasitic Infections
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108035/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.3.1208-1215.1998
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