Expression of Virulence of Mycobacterium tuberculosis within Human Monocytes: Virulence Correlates with Intracellular Growth and Induction of Tumor Necrosis Factor Alpha but Not with Evasion of Lymphocyte-Dependent Monocyte Effector Functions

We assessed the applicability of an in vitro model of low-level infection of human monocytes to the characterization of the virulence of strains of the Mycobacterium tuberculosis family. Peripheral blood monocytes were infected at a 1:1 ratio with the virulent M. tuberculosis strain H37Rv, the aviru...

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izdano v:	Infect Immun
Principais autores:	Silver, Richard F., Li, Qing, Ellner, Jerrold J.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1998
Teme:	Host Response and Inflammation
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488413/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.3.1190-1199.1998
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