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Expression of Virulence of Mycobacterium tuberculosis within Human Monocytes: Virulence Correlates with Intracellular Growth and Induction of Tumor Necrosis Factor Alpha but Not with Evasion of Lymphocyte-Dependent Monocyte Effector Functions

We assessed the applicability of an in vitro model of low-level infection of human monocytes to the characterization of the virulence of strains of the Mycobacterium tuberculosis family. Peripheral blood monocytes were infected at a 1:1 ratio with the virulent M. tuberculosis strain H37Rv, the aviru...

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Detalles Bibliográficos
Main Authors: Silver, Richard F., Li, Qing, Ellner, Jerrold J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC108033/
https://ncbi.nlm.nih.gov/pubmed/9488413
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