Listeria monocytogenes Invasion of Epithelial Cells Requires the MEK-1/ERK-2 Mitogen-Activated Protein Kinase Pathway

PD98059, a specific inhibitor of MEK-1 mitogen-activated protein (MAP) kinase kinase, blocked Listeria monocytogenes invasion into HeLa epithelial cells. The effects of PD98059 were reversible, as adherent extracellular bacteria were internalized upon removal of the drug. Previously, we reported tha...

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Pubblicato in:	Infect Immun
Autori principali:	Tang, Patrick, Sutherland, Claire L., Gold, Michael R., Finlay, B. Brett
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Molecular and Cellular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.3.1106-1112.1998
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