Listeria monocytogenes Invasion of Epithelial Cells Requires the MEK-1/ERK-2 Mitogen-Activated Protein Kinase Pathway

PD98059, a specific inhibitor of MEK-1 mitogen-activated protein (MAP) kinase kinase, blocked Listeria monocytogenes invasion into HeLa epithelial cells. The effects of PD98059 were reversible, as adherent extracellular bacteria were internalized upon removal of the drug. Previously, we reported tha...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Tang, Patrick, Sutherland, Claire L., Gold, Michael R., Finlay, B. Brett
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.3.1106-1112.1998
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