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Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes
From insects to mammals, metallothionein genes are induced in response to heavy metal load by the transcription factor MTF-1, which binds to short DNA sequence motifs, termed metal response elements (MREs). Here we describe a novel and seemingly paradoxical role for MTF-1 in Drosophila in that it al...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1080128/ https://ncbi.nlm.nih.gov/pubmed/15833915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1301805 |
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