Dexamethasone inhibits the HSV-tk/ ganciclovir bystander effect in malignant glioma cells

BACKGROUND: HSV-tk/ ganciclovir (GCV) gene therapy has been extensively studied in the setting of brain tumors and largely relies on the bystander effect. Large studies have however failed to demonstrate any significant benefit of this strategy in the treatment of human brain tumors. Since dexametha...

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Detaylı Bibliyografya
Asıl Yazarlar: Robe, Pierre A, Nguyen-Khac, Minh, Jolois, Olivier, Rogister, Bernard, Merville, Marie-Paule, Bours, Vincent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2005
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1080125/
https://ncbi.nlm.nih.gov/pubmed/15804364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-32
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