Dexamethasone inhibits the HSV-tk/ ganciclovir bystander effect in malignant glioma cells

BACKGROUND: HSV-tk/ ganciclovir (GCV) gene therapy has been extensively studied in the setting of brain tumors and largely relies on the bystander effect. Large studies have however failed to demonstrate any significant benefit of this strategy in the treatment of human brain tumors. Since dexametha...

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Bibliografiska uppgifter
Huvudupphovsmän: Robe, Pierre A, Nguyen-Khac, Minh, Jolois, Olivier, Rogister, Bernard, Merville, Marie-Paule, Bours, Vincent
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2005
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1080125/
https://ncbi.nlm.nih.gov/pubmed/15804364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-32
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