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Identification of Linked Legionella pneumophila Genes Essential for Intracellular Growth and Evasion of the Endocytic Pathway

Legionella pneumophila replicates within a specialized phagosome in cultured cells, a function necessary for its pathogenicity. The replicative phagosome lacks membrane marker proteins, such as the glycoprotein LAMP-1, that are indicators of the normal endocytic pathway. We describe the isolation of...

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Andrews, Helene L., Vogel, Joseph P., Isberg, Ralph R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108001/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488381/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.3.950-958.1998
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