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Identification of Linked Legionella pneumophila Genes Essential for Intracellular Growth and Evasion of the Endocytic Pathway

Legionella pneumophila replicates within a specialized phagosome in cultured cells, a function necessary for its pathogenicity. The replicative phagosome lacks membrane marker proteins, such as the glycoprotein LAMP-1, that are indicators of the normal endocytic pathway. We describe the isolation of...

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Bibliografiska uppgifter
Huvudupphovsmän: Andrews, Helene L., Vogel, Joseph P., Isberg, Ralph R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC108001/
https://ncbi.nlm.nih.gov/pubmed/9488381
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