Genotyping DNA pools on microarrays: Tackling the QTL problem of large samples and large numbers of SNPs

BACKGROUND: Quantitative trait locus (QTL) theory predicts that genetic influence on complex traits involves multiple genes of small effect size. To detect QTL associations of small effect size, large samples and systematic screens of thousands of DNA markers are required. An efficient solution is t...

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Bibliographische Detailangaben
Hauptverfasser: Meaburn, Emma, Butcher, Lee M, Liu, Lin, Fernandes, Cathy, Hansen, Valerie, Al-Chalabi, Ammar, Plomin, Robert, Craig, Ian, Schalkwyk, Leonard C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2005
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1079828/
https://ncbi.nlm.nih.gov/pubmed/15811185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-52
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