Genotyping DNA pools on microarrays: Tackling the QTL problem of large samples and large numbers of SNPs

BACKGROUND: Quantitative trait locus (QTL) theory predicts that genetic influence on complex traits involves multiple genes of small effect size. To detect QTL associations of small effect size, large samples and systematic screens of thousands of DNA markers are required. An efficient solution is t...

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Библиографические подробности
Главные авторы: Meaburn, Emma, Butcher, Lee M, Liu, Lin, Fernandes, Cathy, Hansen, Valerie, Al-Chalabi, Ammar, Plomin, Robert, Craig, Ian, Schalkwyk, Leonard C
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2005
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1079828/
https://ncbi.nlm.nih.gov/pubmed/15811185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-52
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