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Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies

BACKGROUND: Genetic influences underpinning complex traits are thought to involve multiple quantitative trait loci (QTLs) of small effect size. Detection of such QTL associations requires systematic screening of large numbers of DNA markers within large sample populations. Using pooled DNA on SNP mi...

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Библиографические подробности
Главные авторы: Docherty, Sophia J, Butcher, Lee M, Schalkwyk, Leonard C, Plomin, Robert
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925094/
https://ncbi.nlm.nih.gov/pubmed/17610740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-214
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