Mutations of PIK3CA in gastric adenocarcinoma

BACKGROUND: Activation of the phosphatidylinositol 3-kinase (PI3K) through mutational inactivation of PTEN tumour suppressor gene is common in diverse cancer types, but rarely reported in gastric cancer. Recently, mutations in PIK3CA, which encodes the p110α catalytic subunit of PI3K, have been iden...

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Hlavní autoři: Li, Vivian Sze Wing, Wong, Chi Wai, Chan, Tsun Leung, Chan, Agnes Sze Wah, Zhao, Wei, Chu, Kent-Man, So, Samuel, Chen, Xin, Yuen, Siu Tsan, Leung, Suet Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1079799/
https://ncbi.nlm.nih.gov/pubmed/15784156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-29
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