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Targeted and restricted complement activation on acrosome-reacted spermatozoa

A specific hypoglycosylated isoform of the complement regulator membrane cofactor protein (MCP; CD46) is expressed on the inner acrosomal membrane (IAM) of spermatozoa. This membrane is exposed after the acrosome reaction, an exocytosis event that occurs upon contact with the zona pellucida. We init...

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Autors principals: Riley-Vargas, Rebecca C., Lanzendorf, Susan, Atkinson, John P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1077172/
https://ncbi.nlm.nih.gov/pubmed/15849610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523213
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