The Escherichia coli cmlA Gene Encodes the Multidrug Efflux Pump Cmr/MdfA and Is Responsible for Isopropyl-β-d-Thiogalactopyranoside Exclusion and Spectinomycin Sensitivity

Expression of cloned genes from isopropyl-β-d-thiogalactopyranoside (IPTG)-regulated promoters is lowered when the Escherichia coli CmlA/Cmr/MdfA efflux pump is overexpressed, probably due to IPTG exclusion from the cytoplasm. The previously reported cmlA1 mutation confers a similar phenotype. cmlA1...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Autores principales:	Bohn, Chantal, Bouloc, Philippe
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Materias:	Genetics and Molecular Biology
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107689/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.22.6072-6075.1998
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