The Escherichia coli cmlA Gene Encodes the Multidrug Efflux Pump Cmr/MdfA and Is Responsible for Isopropyl-β-d-Thiogalactopyranoside Exclusion and Spectinomycin Sensitivity

Expression of cloned genes from isopropyl-β-d-thiogalactopyranoside (IPTG)-regulated promoters is lowered when the Escherichia coli CmlA/Cmr/MdfA efflux pump is overexpressed, probably due to IPTG exclusion from the cytoplasm. The previously reported cmlA1 mutation confers a similar phenotype. cmlA1...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Bohn, Chantal, Bouloc, Philippe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107689/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.22.6072-6075.1998
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!