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Escherichia coli DNA Topoisomerase I and Suppression of Killing by Tn5 Transposase Overproduction: Topoisomerase I Modulates Tn5 Transposition

Tn5 transposase (Tnp) overproduction is lethal to Escherichia coli. The overproduction causes cell filamentation and abnormal chromosome segregation. Here we present three lines of evidence strongly suggesting that Tnp overproduction killing is due to titration of topoisomerase I. First, a suppresso...

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Bibliografiset tiedot
Päätekijät: Yigit, Hesna, Reznikoff, William S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC107659/
https://ncbi.nlm.nih.gov/pubmed/9811643
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