Escherichia coli DNA Topoisomerase I and Suppression of Killing by Tn5 Transposase Overproduction: Topoisomerase I Modulates Tn5 Transposition

Tn5 transposase (Tnp) overproduction is lethal to Escherichia coli. The overproduction causes cell filamentation and abnormal chromosome segregation. Here we present three lines of evidence strongly suggesting that Tnp overproduction killing is due to titration of topoisomerase I. First, a suppresso...

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Detaylı Bibliyografya

Yayımlandı:	J Bacteriol
Asıl Yazarlar:	Yigit, Hesna, Reznikoff, William S.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1998
Konular:	Plasmids and Transposons
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811643/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.22.5866-5874.1998
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