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Deletion of the Second Immunoglobulin-Like Domain of Nectin-1 Alters Its Intracellular Processing and Localization and Ability To Mediate Entry of Herpes Simplex Virus

Nectin-1 is an immunoglobulin (Ig)-like entry receptor for herpes simplex virus (HSV). Like other nectins, nectin-1 forms dimers and mediates cell adhesion through interactions with other nectins. We constructed a second-domain deletion mutant of nectin-1 (nectin-1-Δ2) to examine the role of the sec...

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Autors principals: Struyf, Frank, Plate, Aileen E., Spear, Patricia G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075719/
https://ncbi.nlm.nih.gov/pubmed/15731277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3841-3845.2005
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