A Noninfectious Simian/Human Immunodeficiency Virus DNA Vaccine That Protects Macaques against AIDS

Simian/human immunodeficiency virus SHIV(KU2) replicates with extremely high titers in macaques. In order to determine whether the DNA of the viral genome could be used as a vaccine if the DNA were rendered noninfectious, we deleted the reverse transcriptase gene from SHIV(KU2) and inserted this DNA...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Singh, Dinesh K., Liu, Zhenqian, Sheffer, Darlene, Mackay, Glenn A., Smith, Marilyn, Dhillon, Sukhbir, Hegde, Ramakrishna, Jia, Fenglan, Adany, Istvan, Narayan, Opendra
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075712/
https://ncbi.nlm.nih.gov/pubmed/15731236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3419-3428.2005
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge