The E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in Swine

To identify genetic determinants of classical swine fever virus (CSFV) virulence and host range, chimeras of the highly pathogenic Brescia strain and the attenuated vaccine strain CS were constructed and evaluated for viral virulence in swine. Upon initial screening, only chimeras 138.8v and 337.14v...

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Main Authors: Risatti, G. R., Borca, M. V., Kutish, G. F., Lu, Z., Holinka, L. G., French, R. A., Tulman, E. R., Rock, D. L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075681/
https://ncbi.nlm.nih.gov/pubmed/15731272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3787-3796.2005
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