Identification of Sites in Adenovirus Hexon for Foreign Peptide Incorporation

Adenovirus type 5 (Ad5) is one of the most promising vectors for gene therapy applications. Genetic engineering of Ad5 capsid proteins has been employed to redirect vector tropism, to enhance infectivity, or to circumvent preexisting host immunity. As the most abundant capsid protein, hexon modifica...

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Bibliographic Details
Main Authors: Wu, Hongju, Han, Tie, Belousova, Natalya, Krasnykh, Victor, Kashentseva, Elena, Dmitriev, Igor, Kataram, Manjula, Mahasreshti, Parameshwar J., Curiel, David T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2005
Subjects:
Gene Delivery
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075677/
https://ncbi.nlm.nih.gov/pubmed/15731232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3382-3390.2005
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