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Identification of Sites in Adenovirus Hexon for Foreign Peptide Incorporation

Adenovirus type 5 (Ad5) is one of the most promising vectors for gene therapy applications. Genetic engineering of Ad5 capsid proteins has been employed to redirect vector tropism, to enhance infectivity, or to circumvent preexisting host immunity. As the most abundant capsid protein, hexon modifica...

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Détails bibliographiques
Auteurs principaux: Wu, Hongju, Han, Tie, Belousova, Natalya, Krasnykh, Victor, Kashentseva, Elena, Dmitriev, Igor, Kataram, Manjula, Mahasreshti, Parameshwar J., Curiel, David T.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1075677/
https://ncbi.nlm.nih.gov/pubmed/15731232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.6.3382-3390.2005
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