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Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin

Mithramycin is an antitumor polyketide drug produced by Streptomyces argillaceus that contains two deoxysugar chains, a disaccharide consisting of two d-olivoses and a trisaccharide consisting of a d-olivose, a d-oliose, and a d-mycarose. From a cosmid clone (cosAR3) which confers resistance to mith...

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Main Authors: Fernández, Ernestina, Weißbach, Ulrike, Reillo, César Sánchez, Braña, Alfredo F., Méndez, Carmen, Rohr, Jürgen, Salas, José A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 1998
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC107519/
https://ncbi.nlm.nih.gov/pubmed/9733697
תגים: הוספת תג
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