Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin

Mithramycin is an antitumor polyketide drug produced by Streptomyces argillaceus that contains two deoxysugar chains, a disaccharide consisting of two d-olivoses and a trisaccharide consisting of a d-olivose, a d-oliose, and a d-mycarose. From a cosmid clone (cosAR3) which confers resistance to mith...

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Библиографические подробности

Опубликовано в::	J Bacteriol
Главные авторы:	Fernández, Ernestina, Weißbach, Ulrike, Reillo, César Sánchez, Braña, Alfredo F., Méndez, Carmen, Rohr, Jürgen, Salas, José A.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1998
Предметы:	Genetics and Molecular Biology
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107519/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.18.4929-4937.1998
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